Anti-PIH1D1 antibody (bs-4273R)

Anti-PIH1D1 antibody 

DATASHEET

Host:Rabbit

Target Protein:PIH1D1

IR:Immunogen Range:91-190/290

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:55011

Swiss Prot:Q9NWS0

Source:KLH conjugated synthetic peptide derived from human PIH1D1/NOP17:91-190/290 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:PIH1D1 is a phylogenetically conserved protein essential for efficient processing of pre-rRNA through its association with a class of small nucleolar RNAs (snoRNAs) during ribosomal biogenesis. SnoRNAs are associated in ribonucleoprotein particles localized to the nucleolus. Nop17 is a 290 amnio acid unstable protein that is stabilized through an interaction with HSP 90?/∫. Nop17 interacts with a core box C/D snoRNP protein Nop58, indicating a function of Nop17 in mediating the nucleolar retention or proper assembly of the box C/D snoRNP. A mutation in NOP17 gene may lead to a temperature-sensitive phenotype along with delocalization of key Nop proteins that are essential for snoRNP assembly.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.