Anti-RAP1GAP antibody (bs-2918R)

Anti-RAP1GAP antibody 

DATASHEET

Host:Rabbit

Target Protein:RAP1GAP

IR:Immunogen Range:451-550/663

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5909

Swiss Prot:P47736

Source:KLH conjugated synthetic peptide derived from human RAP1GAP.:451-550/663 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:RAP1GAP, an 85/95kDa protein, is a member of a family of GAPs specific for Rap1. Though to be an important tumor suppressor, Rap1GAP has no sequence homology with other GAPs such as RasGAP, RanGAP and RhoGAP. Purified as a cytosolic and membrane-bound protein, both isoforms consist of two monomers each contain a dimerization and a catalytic domain. Mutations in the GAP domain of the tumor suppressor tuberin, can cause benign tumor phenotype tuberous sclerosis. There are 2 isoforms produced by alternative splicing.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.