Anti-FES antibody
| 英文名称 | FES |
| 中文名称 | 原癌基因酪氨酸蛋白激酶FES抗体 |
| 别 名 | c-fes/fps protein; cFES; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami; Feline sarcoma oncogene; FPS; Oncogene FES; Oncogene FES feline sarcoma virus; Proto oncogene tyrosine protein kinase Fes/Fps; proto-oncogene tyrosine-protein kinase Fes/Fps. |
DATASHEET
Host:Rabbit
Target Protein:FES
IR:Immunogen Range:121-220/822
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2242
Swiss Prot:P07332
Source:KLH conjugated synthetic peptide derived from human FES:121-220/822
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
好评度