Anti-ASAH2 antibody
| 英文名称 | ASAH2 |
| 中文名称 | 酰基鞘氨醇脱酰酶2抗体 |
| 别 名 | Acylsphingosine deacylase 2; ASAH2; ASAH2_HUMAN; BCDase; hCD; HNAC1; LCDase; MGC129777; mitochondrial ceramidase; N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2; N acylsphingosine amidohydrolase 2; N CDase; N-acylsphingosine amidohydrolase 2; N-CDase; NCDase; Neutral ceramidase soluble form; Non lysosomal ceramidase; Non-lysosomal ceramidase. |
DATASHEET
Host:Rabbit
Target Protein:ASAH2
IR:Immunogen Range:701-780/780
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:56624
Swiss Prot:Q9NR71
Source:KLH conjugated synthetic peptide derived from human ASAH2:701-780/780
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
好评度