Anti-FGFR5 antibody
| 英文名称 | FGFR5 |
| 中文名称 | 成纤维细胞生长因子受体5抗体 |
| 别 名 | FGF homologous factor receptor; FGF receptor like protein 1; FGFR 5; FGFR like protein; FGFR5; FGFRL1; FHFR; Fibroblast growth factor receptor 5; Fibroblast growth factor receptor like 1; FGRL1_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:FGFR5
IR:Immunogen Range:231-330/504
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:53834
Swiss Prot:Q8N441
Source:KLH conjugated synthetic peptide derived from human FGFR5/FGFRL1:231-330/504
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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