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Anti-APBB1 interacting protein 1 antibody (bs-6172R)

Anti-APBB1 interacting protein 1 antibody (bs-6172R)

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Anti-APBB1 interacting protein 1 antibody 

英文名称APBB1 interacting protein 1
中文名称β淀粉样蛋白前体结合蛋白B-1抗体
别    名AB1IP; Amyloid beta A4 precursor protein binding family B member 1 interacting protein; Amyloid beta precursor protein binding family B member 1; APBB1 interacting protein 1; OTTHUMP00000019344; PREL 1; PREL1; Proline rich EVH1 ligand 1; Proline rich protein 73; Rap1 GTP interacting adapter molecule; RAP1 interacting adaptor molecule; RARP 1; RARP1; Retinoic acid responsive proline rich protein 1; AB1IP_HUMAN.  

DATASHEET

Host:Rabbit

Target Protein:APBB1 interacting protein 1

IR:Immunogen Range:301-400/666

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:54518

Swiss Prot:Q7Z5R6

Source:KLH conjugated synthetic peptide derived from human RIAM/APBB1 interacting protein 1:301-400/666 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a gene that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

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