Anti-ANGPTL5 antibody (bs-7046R)

Anti-ANGPTL5 antibody

DATASHEET

Host:Rabbit

Target Protein:ANGPTL5

IR:Immunogen Range:301-388/388

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:253935

Swiss Prot:Q86XS5

Source:KLH conjugated synthetic peptide derived from human ANGPTL5:301-388/388 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in adult heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Chicken
Pig
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.