Anti-NOC2L antibody
英文名称 | NOC2L |
中文名称 | NOC2家族样蛋白抗体 |
别 名 | NIR; NOC2 like; Novel INHAT (inhibitor of histone acetyltransferase) repressor; Nucleolar complex associated 2 homolog (S. cerevisiae); Protein NOC2 homolog; NOC2L_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:NOC2L
IR:Immunogen Range:251-350/749
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:26155
Swiss Prot:Q9Y3T9
Source:KLH conjugated synthetic peptide derived from human NOC2L:251-350/749
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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