Anti-Cyclin L antibody (bs-7888R)

Anti-Cyclin L antibody 

DATASHEET

Host:Rabbit

Target Protein:Cyclin L

IR:Immunogen Range:351-450/526

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:57018

Swiss Prot:Q9UK58

Source:KLH conjugated synthetic peptide derived from human Cyclin L/CCNL1:351-450/526 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.
Tissue specificity;Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
Chimpanzee
mpanzee.

For research use only. Not intended for diagnostic or therapeutic use.