Anti-MBC1 antibody
| 英文名称 | MBC1 |
| 中文名称 | 膀胱癌突变蛋白1抗体 |
| 别 名 | MBC1; Mutated in bladder cancer protein 1; coiled coil domain containing 112; coiled-coil domain containing 112; MBC1; CC112_HUMAN; CCDC112; Coiled coil domain containing protein 112; Coiled-coil domain-containing protein 112; Mutated in bladder cancer 1; Mutated in bladder cancer protein 1. |
DATASHEET
Host:Rabbit
Target Protein:MBC1
IR:Immunogen Range:301-400/446
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:153733
Swiss Prot:Q8NEF3
Source:KLH conjugated synthetic peptide derived from human CCDC112/MBC1:301-400/446
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CCDC112, also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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