Anti-UBE2M antibody
英文名称 | UBE2M |
中文名称 | 泛素蛋白连接酶M抗体 |
别 名 | hUbc12; NEDD8 carrier protein; NEDD8 conjugating enzyme Ubc12; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC-RS2; UBC12; UBC12_HUMAN; ube2m; ubiquitin carrier protein M; Ubiquitin conjugating enzyme E2 M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-protein ligase M; yeast UBC12 homolog. |
DATASHEET
Host:Rabbit
Target Protein:UBE2M
IR:Immunogen Range:1-100/183
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9040
Swiss Prot:P61081
Source:KLH conjugated synthetic peptide derived from human UBE2M:1-100/183
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
xenopuslaevis.
For research use only. Not intended for diagnostic or therapeutic use.
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