Anti-Factor XI light chain antibody (bs-9502R)

Anti-Factor XI light chain antibody

DATASHEET

Host:Rabbit

Target Protein:Factor XI light chain

IR:Immunogen Range:451-550/625

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2160

Swiss Prot:P03951

Source:KLH conjugated synthetic peptide derived from human Coagulation factor XIa light chain:451-550/625 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Dog
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.