Anti-MARCH1 antibody
| 英文名称 | MARCH1 |
| 中文名称 | 膜相关环指蛋白1抗体 |
| 别 名 | E3 ubiquitin protein ligase MARCH1; E3 ubiquitin-protein ligase MARCH1; MARCH 1; MARCH-I; March1; MARH1_HUMAN; Membrane associated RING CH protein I; Membrane associated ring finger (C3HC4) 1; Membrane associated RING finger protein 1; Membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; RING finger protein 171; RNF171. |
DATASHEET
Host:Rabbit
Target Protein:MARCH1
IR:Immunogen Range:101-200/289
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:55016
Swiss Prot:Q8TCQ1
Source:KLH conjugated synthetic peptide derived from human MARCH1:101-200/289
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, downregulates their cell surface localization thus sequestering them in the intracellular endosomal system.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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