Anti-EDRF1 antibody
英文名称 | EDRF1 |
中文名称 | 红细胞分化相关因子1抗体 |
别 名 | C10orf137 protein; Chromosome 10 open reading frame 137; EDRF1; Erythroid differentiation related factor 1; EDRF1_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:EDRF1
IR:Immunogen Range:101-200/1238
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:26098
Swiss Prot:Q3B7T1
Source:KLH conjugated synthetic peptide derived from Human EDRF1/C10orf137:101-200/1238
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
好评度