Anti-Hepatitis C Virus RNA-directed RNA polymerase antibody (bs-4858R)

Anti-Hepatitis C Virus RNA-directed RNA polymerase antibody

DATASHEET

Host:Rabbit

Target Protein:Hepatitis C Virus RNA-directed RNA polymerase

IR:Immunogen Range:2501-2600/3010

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:951475

Swiss Prot:P26664

Source:KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase:2501-2600/3010 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins, and several non-structural proteins necessary for viral replication, of which NS5B is one. NS5B RNA-dependant RNA polymerase is responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication. Hepatitis C virus (HCV) can cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. At present there is no vaccine effective against HCV. Host membrane insertion occurs after processing by the NS3 protease.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)

Cross Reactive Species:HCV.

For research use only. Not intended for diagnostic or therapeutic use.