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Anti-PAPOL A+B+G antibody (bs-9435R)

Anti-PAPOL A+B+G antibody (bs-9435R)

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Anti-PAPOL A+B+G antibody

英文名称PAPOL A+B+G
中文名称多聚合酶α/β/γ抗体
别    名PAPOL A/B/G; PAP alpha/beta/gamma; PapIII; MGC5378; PAP alpha; PAP beta; PAP gamma; PAP; PAP-alpha; PAP-beta; PAP-gamma; PAPOLA; PAPOLB; PAPOLG; PAPOA_HUMAN; PAPOB_HUMAN; PAPOG_HUMAN; Plap; poly(A) polymerase alpha; Polynucleotide adenylyltransferase alpha; poly(A) polymerase beta (testis specific); poly(A) polymerase beta; polynucleotide adenylyltransferase beta; TPAP; Testis-specific poly(A) polymerase.  

DATASHEET

Host:Rabbit

Target Protein:PAPOL A+B+G

IR:Immunogen Range:81-190/745

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:10914

Swiss Prot:P51003

Source:KLH conjugated synthetic peptide derived from human PAPOLA:81-190/745 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A) tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-beta plays a critical role in male germ cell production. PAP-beta-deficient transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-beta maps to chromosome 7p22.3.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
.

For research use only. Not intended for diagnostic or therapeutic use.

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