Anti-HCN2 antibody (bs-9858R)

Anti-HCN2 antibody

DATASHEET

Host:Rabbit

Target Protein:HCN2

IR:Immunogen Range:288-350/889

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:610

Swiss Prot:Q9UL51

Source:KLH conjugated synthetic peptide derived from human HCN2:288-350/889 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1–4), each with a core transmembrane segment domain and a carboJNC-terminal 120 amino-acid cyclic nucleotide-binding domain motif (1). HCN channels are expressed in the brain, heart, thalamus and testis (1). The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart (1). The genes encoding human HCN1 and HCN2 map to chromosomes 5 and 19p13.3, respectively (2,3). The genes encoding HCN3 and HCN4 map to chromosomes 1q21.3 and 15q24-q25, respectively (4,5).

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:50-200)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.