Anti-SISP1 antibody
| 英文名称 | SISP1 |
| 中文名称 | 应激诱导分泌蛋白1抗体 |
| 别 名 | C10orf54; VISTA_HUMAN; Platelet receptor Gi24; stress induced secreted protein 1; UNQ730/PRO1412; V-type immunoglobulin domain-containing suppressor of T-cell activation; Stress-induced secreted protein-1; Sisp-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; B7-H5; B7H5; DD1alpha; GI24; PD-1H; PP2135; VISTA. |
DATASHEET
Host:Rabbit
Target Protein:SISP1
IR:Immunogen Range:21-120/311
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:64115
Swiss Prot:Q9H7M9
Source:KLH conjugated synthetic peptide derived from human SISP1/GI24:21-120/311
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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