Anti-C20orf11 antibody
英文名称 | C20orf11 |
中文名称 | 20号染色体开放阅读框11抗体 |
别 名 | Chromosome 20 open reading frame 11; CT011_HUMAN; Protein C20orf11; Twa1; Two hybrid associated protein 1; Two hybrid-associated protein 1 with Ran BP-M; Two hybrid associated protein 1 with RanBPM; Two hybrid-associated protein 1 with RanBPM. |
DATASHEET
Host:Rabbit
Target Protein:C20orf11
IR:Immunogen Range:1-100/228
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:54994
Swiss Prot:Q9NWU2
Source:KLH conjugated synthetic peptide derived from human TWA1/C20orf11:1-100/228
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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