Anti-NTAL antibody (bs-9558R)

Anti-NTAL antibody 

DATASHEET

Host:Rabbit

Target Protein:NTAL

IR:Immunogen Range:1-100/243

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:7462

Swiss Prot:Q9GZY6

Source:KLH conjugated synthetic peptide derived from human NTAL:1-100/243 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Non-T cell activation linker (NTAL), a transmembrane adaptor protein, is also designated membrane-associated adapter molecule, Williams-Beuren syndrome chromosome region 15 protein or LAB (linker of activated B cells). NTAL is present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells, and in monocytes and mast cells, but not in resting T lymphocytes. NTAL becomes rapidly tyrosine-phosphorylated upon cross-linking of the B cell receptor (BCR) or of high-affinity Fc g and Fc e receptors of myeloid cells and then associates with the cytoplasmic signaling molecules. NTAL is highly expressed in spleen, lymph node germinal centers and peripheral blood lymphocytes. Defects in the gene encoding for NTAL may cause the musculo-skeletal and cardio-vascular abnormalities that characterize the rare developmental disorder Williams-Beuren syndrome (WBS).

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
.

For research use only. Not intended for diagnostic or therapeutic use.