Anti-PCDHB15 antibody (bs-11134R)

Anti-PCDHB15 antibody

DATASHEET

Host:Rabbit

Target Protein:PCDHB15

IR:Immunogen Range:121-220/787

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:56121

Swiss Prot:Q9Y5E8

Source:KLH conjugated synthetic peptide derived from human PCDHB15.:121-220/787 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. Pcdhb22 (protocadherin beta 22), also known as PcdhbV or Pcdhb15, is a 794 amino acid murine protein that is thought to function as a calcium-dependent cell-adhesion protein. Pcdhb22 is a homolog of human PCDHB15 (protocadherin beta 15), a 787 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB15) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.