Anti-SPRR1a antibody
英文名称 | SPRR1a |
中文名称 | 角质蛋白α抗体 |
别 名 | 19 kDa pancornulin; Cornifin A; Cornifin alpha; CornifinA; Small proline rich protein 1A; Small proline rich protein IA; spr; SPR IA; SPRK; SPRR 1a; SPRR1A protein; SPR1A_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:SPRR1a
IR:Immunogen Range:21-89/89
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6698
Swiss Prot:P35321
Source:KLH conjugated synthetic peptide derived from human SPRR1a/Cornifin A:21-89/89
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The small proline rich protein (SPRR) gene family encodes a conserved group of cornified envelope (CE) proteins that are part of the human epidermal differentiation complex (EDC). The formation of the cornified envelope during the late stages of epidermal differentiation is essential for epidermal barrier function and protects the body against environmental attack and water loss. Additionally, the expression of SPRR proteins is linked to keratinocyte terminal differentiation. The SPRR gene family, namely comprises three subclasses of genes, SPRR1 (which contains two members), SPRR2 (which contains eight members) and SPRR3 (which contains one member). SPRR1 is found predominantly in follicular epidermis and oral mucosa, SPRR2 is expressed coherently in follicular and interfollicular epidermis and SPRR3 is absent in epidermis and strongly expressed in internal squamous.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
.
For research use only. Not intended for diagnostic or therapeutic use.
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