Anti-Visual Arrestin antibody (bs-8710R)

Anti-Visual Arrestin antibody

DATASHEET

Host:Rabbit

Target Protein:Visual Arrestin

IR:Immunogen Range:141-240/405

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6295

Swiss Prot:P10523

Source:KLH conjugated synthetic peptide derived from human Visual Arrestin:141-240/405 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Members of the Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors, and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Visual Arrestin, also known as Arrestin, retinal S-antigen or S-Arrestin, is a major soluble photoreceptor protein that regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual Arrestin is expressed in retinal photoreceptor cells and the pineal gland. Visual Arrestin is the major pathogenic autoantigen in inflammatory eye disease, such as uveoretinitis and Oguchi disease, a rare autosomal recessive form of night blindness.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
cpw.

For research use only. Not intended for diagnostic or therapeutic use.