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Anti-HSPABP/HIP/HSC70 Interacting Protein HIP antibody (bs-11271R)

Anti-HSPABP/HIP/HSC70 Interacting Protein HIP antibody (bs-11271R)

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Anti-HSPABP/HIP/HSC70 Interacting Protein HIP antibody

英文名称HSPABP/HIP/HSC70 Interacting Protein HIP
中文名称热休克蛋白70相互作用蛋白抗体
别    名AAG 2; AAG2; Aging associated protein 2; F10A1_HUMAN; FAM10A1; FAM10A4; FLJ27260; Heat shock 70kD protein binding protein; HIP; HOP; Hsc70 interacting protein; Hsc70-interacting protein; Hsp70 interacting protein; HSPABP 1; HSPABP; HSPABP1; MGC129952; OTTHUMP00000028873; P48 antibody PRO0786; Progesterone receptor associated p48 protein; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY REN 33; Renal carcinoma antigen NY-REN-33; SNC 6; SNC6; ST 13; ST13; Suppression of tumorigenicity 13; Suppression of tumorigenicity 13 (colon carcinoma); Suppression of tumorigenicity 13 protein; Suppression of tumorigenicity protein 13. 

DATASHEET

Host:Rabbit

Target Protein:HSPABP/HIP/HSC70 Interacting Protein HIP

IR:Immunogen Range:181-280/369

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6767

Swiss Prot:P50502

Source:KLH conjugated synthetic peptide derived from human HSPABP:181-280/369 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
.

For research use only. Not intended for diagnostic or therapeutic use.

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