Anti-Piccolo antibody (bs-11354R)

Anti-Piccolo antibody 

DATASHEET

Host:Rabbit

Target Protein:Piccolo

IR:Immunogen Range:4951-5056/5056

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:27445

Swiss Prot:Q9Y6V0

Source:KLH conjugated synthetic peptide derived from human Piccolo:4951-5056/5056 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a similar distribution and colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
.

For research use only. Not intended for diagnostic or therapeutic use.