Anti-Utrophin antibody
| 英文名称 | Utrophin |
| 中文名称 | 肌营养不良蛋白相关蛋白1抗体 |
| 别 名 | DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin |
DATASHEET
Host:Rabbit
Target Protein:Utrophin
IR:Immunogen Range:3110-3156/3433
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7402
Swiss Prot:P46939
Source:KLH conjugated synthetic peptide derived from human Utrophin:3110-3156/3433
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboJNC terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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