Anti-EBF2 antibody
| 英文名称 | EBF2 |
| 中文名称 | 早期B淋巴细胞因子2抗体 |
| 别 名 | COE 2; COE2; Collier Olf and EBF 2; Early B cell factor 2; EBF 2; FLJ11500; Metencephalon mesencephalnon olfactory transcription factor 1; O/E 3; O/E3; OE 3; OE3; OLF 1/EBF like 3; Transcription factor COE2; COE2_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:EBF2
IR:Immunogen Range:331-400/575
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:64641
Swiss Prot:Q9HAK2
Source:KLH conjugated synthetic peptide derived from human EBF2:331-400/575
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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