Anti-Prion protein antibody
| 英文名称 | Prion protein |
| 中文名称 | 朊病毒蛋白CD230抗体 |
| 别 名 | Alternative prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; Major prion protein; p27 30; PRIO_HUMAN; Prion related protein; PRIP; PRNP; PrP; PrP27 30; PrP27-30; PrP33-35C; PrPC; PrPSc; Sinc |
DATASHEET
Host:Rabbit
Target Protein:Prion protein
IR:Immunogen Range:23-120/253
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5621
Swiss Prot:P04156
Source:KLH conjugated synthetic peptide derived from human Prion protein PrP/CD230:23-120/253
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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