Anti-Tetanus toxin light chain antibody (bs-10155R)

Anti-Tetanus toxin light chain antibody

DATASHEET

Host:Rabbit

Target Protein:Tetanus toxin light chain

IR:Immunogen Range:365-470/1315

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:24255210

Swiss Prot:P04958

Source:KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin light chain:365-470/1315 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Clostridium tetani E88.

For research use only. Not intended for diagnostic or therapeutic use.