Anti-5HT1E Receptor antibody (bs-12047R)

Anti-5HT1E Receptor antibody

DATASHEET

Host:Rabbit

Target Protein:5HT1E Receptor

IR:Immunogen Range:1-120/365

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3354

Swiss Prot:P28566

Source:KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E:1-120/365 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Pig
Cow
Guinea Pig
.

For research use only. Not intended for diagnostic or therapeutic use.