Anti-phospho-Cyclin E2 (Thr396) antibody
| 英文名称 | phospho-Cyclin E2 (Thr396) |
| 中文名称 | 磷酸化周期素E2抗体 |
| 别 名 | Cyclin E2 (phospho T396); p-Cyclin E2 (phospho T396); phospho-Cyclin E2 (Thr396)(rat) / phospho-Cyclin E2 (Thr393)(mo); Cyclin E2 (phospho T393)(mo); CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cyclin E2; G1/S-specific cyclin E2. |
DATASHEET
Host:Rabbit
Target Protein:phospho-Cyclin E2 (Thr396)
IR:Immunogen Range:LL(p-T)PP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9134
Swiss Prot:O96020
Source:KLH conjugated Synthesised phosphopeptide derived from rat Cyclin E2 around the phosphorylation site of Thr396:LL(p-T)PP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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