Anti-Phospho-EEF2k (Ser359) antibody
英文名称 | Phospho-EEF2k (Ser359) |
中文名称 | 磷酸化真核延伸因子激酶2抗体 |
别 名 | EEF2K (phospho S359); p-EEF2K (phospho S359); Calcium/calmodulin dependent eukaryotic elongation factor 2; Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase; Calmodulin dependent protein kinase III; cb365; eEF 2 kinase; eEF 2K; EEF2K protein; Elongation factor 2 kinase; Eukaryotic elongation factor 2 kinase; kinase eEF2K; SMEF2K; EF2K_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-EEF2k (Ser359)
IR:Immunogen Range:CG(p-S)P
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:29904
Swiss Prot:O00418
Source:KLH conjugated Synthesised phosphopeptide derived from human EEF2k around the phosphorylation site of Ser359:CG(p-S)P
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Eukaryotic elongation factor 2 kinase (EEF2k) previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 (eEf2). Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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