Anti-FMO3 antibody (bs-13186R)

Anti-FMO3 antibody 

DATASHEET

Host:Rabbit

Target Protein:FMO3

IR:Immunogen Range:111-210/532

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2328

Swiss Prot:P31513

Source:KLH conjugated synthetic peptide derived from human FMO3:111-210/532 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The Flavin containing monooJNCgenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oJNCgenates soft nucleophiles such as secondary and tertiary amines. Through its N-oJNCgenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
Monkey
.

For research use only. Not intended for diagnostic or therapeutic use.