Anti-FJNCD6 antibody (bs-13234R)

Anti-FJNCD6 antibody

DATASHEET

Host:Rabbit

Target Protein:FJNCD6

IR:Immunogen Range:15-75/95

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:53826

Swiss Prot:Q9H0Q3

Source:KLH conjugated synthetic peptide derived from human FJNCD6:15-75/95 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The mammalian FJNCD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FJNCDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFJNCD and containing seven invariant and six conserved amino acids. Members of the FJNCD family include FJNCD1 (PLM, phospholemman), FJNCD2 (the g subunit of the Na+/K+-ATPase), FJNCD3 (Mat8, mammary tumor protein), FJNCD4 (CHIF) and FJNCD5 (RIC). FJNCD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FJNCD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FJNCD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.