Anti-phospho-FOXL2 (Ser263) antibody
| 英文名称 | phospho-FOXL2 (Ser263) |
| 中文名称 | 磷酸化叉头蛋白L2抗体 |
| 别 名 | FOXL2 (phospho S263); p-FOXL2 (phospho S263); blepharophimosis; Blepharophimosis epicanthus inversus and ptosis 1; Blepharophimosis epicanthus inversus and ptosis; BPES 1; BPES; BPES1; epicanthus inversus and ptosis 1; forkhead box L2; Forkhead box protein L2; forkhead transcription factor FOXL2; FOX L2; FOXL 2; FOXL2; FOXL2_HUMAN; PFRK; PINTO; POF 3; POF3. |
DATASHEET
Host:Rabbit
Target Protein:phospho-FOXL2 (Ser263)
IR:Immunogen Range:VQ(p-S)MA
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:668
Swiss Prot:P58012
Source:KLH conjugated synthesised phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263:VQ(p-S)MA
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Size:100ul
Concentration:1mg/ml
Applications:
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
.
For research use only. Not intended for diagnostic or therapeutic use.
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