Anti-GANC antibody (bs-13279R)

Anti-GANC antibody

DATASHEET

Host:Rabbit

Target Protein:GANC

IR:Immunogen Range:31-130/914

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2595

Swiss Prot:Q8TET4

Source:KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C:31-130/914 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, α neutral C) is a 914 amino acid protein with α-glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked α-D-glucose residues and releases α-D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.