Anti-phospho-GATA3 (Ser115) antibody
| 英文名称 | phospho-GATA3 (Ser115) |
| 中文名称 | 磷酸化GATA结合蛋白3抗体 |
| 别 名 | GATA3 (phospho S115); p-GATA3 (phospho S115); GATA3 (phospho Ser115); p-GATA3 (Ser115); GATA 3; GATA3; GATA-3; GATA binding factor 3; GATA binding protein 3; HDR; MGC2346; MGC5199; MGC5445; Trans acting T cell specific transcription factor GATA 3. |
DATASHEET
Host:Rabbit
Target Protein:phospho-GATA3 (Ser115)
IR:Immunogen Range:NL(p-S)PF
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2625
Swiss Prot:P23771
Source:KLH conjugated synthesised phosphopeptide derived from human GATA3 around the phosphorylation site of Ser115:NL(p-S)PF
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig
Danio rerio.
For research use only. Not intended for diagnostic or therapeutic use.
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