Anti-NOB1 antibody
| 英文名称 | NOB1 |
| 中文名称 | RNA结合蛋白NOB1抗体 |
| 别 名 | Adenocarcinoma antigen recognized by T lymphocytes 4; ART4; MST158; MSTP158; Nin one binding protein; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); nob1; NOB1_HUMAN; NOB1P; Phosphorylation regulatory protein HP-10; Protein ART-4; Protein ART4; PSMD8 binding protein 1; PSMD8BP1; RNA binding protein NOB1; RNA-binding protein NOB1. |
DATASHEET
Host:Rabbit
Target Protein:NOB1
IR:Immunogen Range:51-150/412
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:28987
Swiss Prot:Q9ULX3
Source:KLH conjugated synthetic peptide derived from human NOB1:51-150/412
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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