Anti-GPCR HM74 antibody
| 英文名称 | GPCR HM74 |
| 中文名称 | G蛋白偶联受体HM74蛋白抗体 |
| 别 名 | G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GPR109B; HCA3; HCAR3; HM74; HM74B; HydroJNCcarboJNClic acid receptor 3; Niacin receptor 2; NIACR2; Nicotinic acid receptor 2; Puma-g; PUMAG; HCAR3_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:GPCR HM74
IR:Immunogen Range:51-150/387
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8843
Swiss Prot:P49019
Source:KLH conjugated synthetic peptide derived from human GPCR HM74:51-150/387
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HM74 is a member of the G protein coupled receptor (GPCR) superfamily. In humans, HM74 is encoded by two different genes (GPR109A and GPR109B) that express two distinct proteins, namely HM74A and HM74B (also known as simply HM74), which are 96% homologous. In mice and rats, only one gene (deisngnated Gpr109a) encodes the HM74 protein. HM74B is a G(i) protein-coupled receptor that mediates the metabolic effects of nicotinic acid. Localizing to the cell membrane, HM74B is highly expressed in adipocytes, immune cells and spleen and, like all members of the GPCR superfamily, contains seven transmembrane domains. HM74B lacks the characteristic N-linked glycosylation sites that are present in other GPCR family members and also shows a more diverged amino acid sequence homology from most family members, implying different ligand specificity
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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