Anti-phospho-c-Abl (Thr754 + Thr735) antibody
| 英文名称 | phospho-c-Abl (Thr754 + Thr735) |
| 中文名称 | 磷酸化非受体酪氨酸激酶c-Abl抗体 |
| 别 名 | phospho-c-Abl(Thr754/Thr735); Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; Abl 1; ABL; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK 7; JTK7; p150; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl; ABL1_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:phospho-c-Abl (Thr754 + Thr735)
IR:Immunogen Range:SV(p-T)LP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:25
Swiss Prot:P00519
Source:KLH conjugated synthetic peptide derived from human c-Abl:SV(p-T)LP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Guinea Pig
.
For research use only. Not intended for diagnostic or therapeutic use.
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