Anti-IFITM2 antibody
| 英文名称 | IFITM2 |
| 中文名称 | 干扰素诱导跨膜蛋白2抗体 |
| 别 名 | 1 8D; Dispanin subfamily A member 2c; DSPA2c; IFITM 2; Interferon induced transmembrane protein 2 (1 8D); IFM2_HUMAN; Interferon induced transmembrane protein 2; Interferon inducible protein 1 8D. |
DATASHEET
Host:Rabbit
Target Protein:IFITM2
IR:Immunogen Range:11-100/132
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10581
Swiss Prot:Q01629
Source:KLH conjugated synthetic peptide derived from human IFITM2:11-100/132
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Size:100ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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