Anti-CHD3 antibody
| 英文名称 | CHD3 |
| 中文名称 | 染色质解旋酶DNA结合蛋白3抗体 |
| 别 名 | 226; 2600010P09Rik; AF020312; ATP dependent helicase CHD3; ATP-dependent helicase Chd3; CHD-3; Chd3; CHD3_HUMAN; Chd7; Chromodomain-helicase-DNA-binding protein 3; hZFH; MGC40857; Mi 2 autoantigen 240 kDa protein; Mi 2a; Mi-2 autoantigen 240 kDa protein; Mi2 ALPHA; Mi2-alpha; Prp7; Prp9 1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like). |
DATASHEET
Host:Rabbit
Target Protein:CHD3
IR:Immunogen Range:1201-1300/2000
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1107
Swiss Prot:Q12873
Source:KLH conjugated synthetic peptide derived from human CHD3:1201-1300/2000
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessiblity to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Chromatin structure alteration may be brought about by the action of ATP-dependent multiprotein complexes. One such complex is the mSin3 corepressor complex, which contains mSin3, the histone deacetylases HDAC1 and HDAC2, the associated proteins SAP 30 and SAP 18, and the autoantigens Mi2-a and Mi2-b.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Sheep
Chimpanzee
.
For research use only. Not intended for diagnostic or therapeutic use.
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