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Anti-Chemokine Receptor D6 antibody (bs-13897R)

Anti-Chemokine Receptor D6 antibody (bs-13897R)

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Anti-Chemokine Receptor D6 antibody

英文名称Chemokine Receptor D6
中文名称趋化因子受体D6抗体
别    名C C chemokine receptor D6; C-C chemokine receptor D6; CC chemokine binding receptor JAB61; CC chemokine receptor D6; CCBP 2; CCBP2; ACKR2_HUMAN; CCR 10; CCR 9; CCR10; CCR9; Chemokine (C C motif) receptor 9; Chemokine (C C) receptor 9; Chemokine binding protein 2; Chemokine binding protein D6; Chemokine C C motif receptor 9; Chemokine C C receptor 9; Chemokine CC motif receptor 9; Chemokine CC receptor 9; Chemokine receptor 9; Chemokine receptor CCR 10; Chemokine receptor CCR 9; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine receptor CCR10; Chemokine receptor CCR9; Chemokine receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR 9; CMKBR9; D6; hD6; MGC126678; MGC138250.

DATASHEET

Host:Rabbit

Target Protein:Chemokine Receptor D6

IR:Immunogen Range:101-200/384

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:1238

Swiss Prot:O00590

Source:KLH conjugated synthetic peptide derived from human Chemokine Receptor D6:101-200/384 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Chemokine Receptor D6 is a member of the C-C (β chemokine) G protein-coupled receptor family. This family is characterized by a pair of adjacent cysteine residues. C-C chemokine receptor family members also include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10, CCXCKR, Bonzo, BOB (brother of Bonzo) and Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to sites of inflammation. Chemokine Receptor D6 acts as a receptor for various C-C type chemokines, including SCYA2/MCP-1, SCY3/MIP-1-α, SCYA5/RANTES and SCYA7/MCP-3. It is expressed primarily in placental tissues and fetal liver, but is also detected in lymphatic endothelial cells, lymph nodes and mucosa of the small and large intestines.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Blank control: Molt4.
Primary Antibody (green line): Rabbit Anti-Chemokine Receptor D6 antibody (bs-13897R-FITC)
Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Dilution: 1μg /test.
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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