Anti-CHTF18 antibody
英文名称 | CHTF18 |
中文名称 | 16号染色体开放阅读框41抗体 |
别 名 | C16orf41; 6030457M03Rik; C16orf41; C321D2.2; C321D2.3; C321D2.4; CHL12; chromosome transmission fidelity factor 18 homolog (S. cerevisiae); Chromosome transmission fidelity protein 18 homolog; chtf18; Ctf18; CTF18_HUMAN; hCTF18; MGC38008; RUVBL. |
DATASHEET
Host:Rabbit
Target Protein:CHTF18
IR:Immunogen Range:301-400/975
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:63922
Swiss Prot:Q8WVB6
Source:KLH conjugated synthetic peptide derived from human CHTF18/C16orf41:301-400/975
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CTF18 is a 975 amino acid protein encoded by the human gene CHTF18. CTF18 is a protein that is structurally related to the Rad24 and RFC (replication factor C) proteins. CTF18 is believed to form a novel RFC complex and functions redundantly with Rad24 in the DNA replication block checkpoint. The CTF18-RFC complex is a seven-subunit structure that consists of the four small subunits of RFC, together with CTF18, DCC1, and CTF8. This RFC complex is responsible for loading the replication clamp PCNA (Proliferating Cell Nuclear Antigen) onto DNA and functions in DNA replication and repair. Regulated unloading of PCNA during the progression and termination of DNA replication does not seem to be a function of the CTF18-RFC complex.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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