Anti-phospho-Cortactin (Tyr421) antibody
| 英文名称 | phospho-Cortactin (Tyr421) |
| 中文名称 | 磷酸化皮层肌动蛋白抗体 |
| 别 名 | Cortactin (phospho Y421); p-Cortactin (phospho Y421); Amplaxin; CTTN; EMS 1; EMS1; FLJ34459; Mammary tumor and squamous cell carcinoma associated; Oncogene EMS1; p80/85 src substrate; Src substrate cortactin; SRC8_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:phospho-Cortactin (Tyr421)
IR:Immunogen Range:PV(p-Y)ED
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2017
Swiss Prot:Q14247
Source:KLH conjugated Synthesised phosphopeptide derived from human Cortactin around the phosphorylation site of Tyr421:PV(p-Y)ED
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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