Anti-DNAJB14 antibody (bs-14372R)

Anti-DNAJB14 antibody

DATASHEET

Host:Rabbit

Target Protein:DNAJB14

IR:Immunogen Range:301-379/379

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:79982

Swiss Prot:Q8TBM8

Source:KLH conjugated synthetic peptide derived from human DNAJB14:301-379/379 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The DnaJ family, one of the largest of all the chaperone families, has evolved with diverse cellular localization and functions. The presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat-shock induced proteins are derived from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for chaperone function. DnaJ family members are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB14 (DnaJ (Hsp40) homolog, subfamily B, member 14) is a 379 amino acid single-pass membrane protein containing one J domain and is thought to act as a co-chaperone. DnaJB14 exists as two alternatively spliced isoforms.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.