Anti-DNAJC1 antibody (bs-14377R)

Anti-DNAJC1 antibody

DATASHEET

Host:Rabbit

Target Protein:DNAJC1

IR:Immunogen Range:451-554/554

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:64215

Swiss Prot:Q96KC8

Source:KLH conjugated synthetic peptide derived from human DNAJC1:451-554/554 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The DnaJ family comprises a group of chaperone proteins that contain a J domain and have diverse cellular localization and functions. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis and are also important mediators of proteolysis and protein degradation. DnaJC1 (DnaJ homolog subfamily C member 1), also designated MTJ1, HTJ1, ERdj1 or DNAJL1, is a 554 amino acid single-pass type I membrane protein found in the membrane of the endoplasmic reticulum, nucleus and microsome. DnaJC1 contains one J domain and two SANT domains, through which it interacts with GRP 78 and AACT, respectively. Via its cytosolic domain, DnaJC1 interacts with ribosomes and likely modulates protein synthesis. The gene encoding DnaJC1 maps to human chromosome 10p12.31 and mouse chromosome 2 A3.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
.

For research use only. Not intended for diagnostic or therapeutic use.