Anti-DNHD1 antibody (bs-14398R)

Anti-DNHD1 antibody

DATASHEET

Host:Rabbit

Target Protein:DNHD1

IR:Immunogen Range:1-200/4753

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:144132

Swiss Prot:Q96M86

Source:KLH conjugated synthetic peptide derived from human DNHD1:1-200/4753 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNHD1 is a 4,753 amino acid member of the dynein heavy chain protein family. Phosphorylated upon DNA damage, DNHD1 contains 12 LRR (leucine-rich) repeats. The gene that encodes DNHD1 maps to human chromosome 11, which contains 135 million base pairs and 1,400 genes.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)

Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.