Anti-EFCAB4A antibody
英文名称 | EFCAB4A |
中文名称 | EFCAB4A蛋白抗体 |
别 名 | EF-CAB4A; Calcium release-activated calcium channel regulator 2B; CRAC channel regulator 2B; CRACR2B; EF-hand calcium-binding domain-containing protein 4A; EFC4A_HUMAN; Efcab4a. |
DATASHEET
Host:Rabbit
Target Protein:EFCAB4A
IR:Immunogen Range:151-250/399
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:283229
Swiss Prot:Q8N4Y2
Source:KLH conjugated synthetic peptide derived from human EFCAB4A:151-250/399
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:EF-CAB4A is a 399 amino acid protein belonging to the EFCAB4 family. Containing two EF-hand domains, EF-CAB4A may be involved in store-operated Ca2+ entry (SOCE). EF-CAB4A exists as three alternatively spliced isoforms, and is encoded by a gene mapping to human chromosome 11p15.5. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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