Anti-ELMOD1 antibody
英文名称 | ELMOD1 |
中文名称 | ELMOD1蛋白抗体 |
别 名 | DKFZp547C176; ELMD1_HUMAN; ELMO domain containing 1; ELMO domain-containing protein 1; ELMO/CED 12 domain containing 1; Elmod1. |
DATASHEET
Host:Rabbit
Target Protein:ELMOD1
IR:Immunogen Range:21-120/334
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:55531
Swiss Prot:Q8N336
Source:KLH conjugated synthetic peptide derived from human ELMOD1:21-120/334
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ELMOD1 is a 334 amino acid protein that contains one ELMO domain and is encoded by a gene that maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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